A traditional herb modified to make it safer. Here's where DGL fits in canine GI care.
Licorice root has been used for digestive support for centuries. But standard licorice contains compounds that can cause significant side effects with sustained use. DGL — deglycyrrhizinated licorice — removes the problematic compounds while retaining the gastric-protective properties.
Most premium pet products are premium prices for ordinary inputs. Here's a working overview of DGL for dogs.
What DGL is
Licorice root from which glycyrrhizin has been removed.
Glycyrrhizin causes mineralocorticoid effects (sodium retention, potassium loss, blood pressure elevation) with sustained use.
DGL retains the flavonoids and other compounds responsible for gastric-protective effects.
Considered safer for extended use than whole licorice.
Gastric-protective effects
May increase mucus production in the stomach.
May increase blood flow to gastric tissue.
May extend the lifespan of mucosal cells.
Anti-inflammatory effects.
Used in human medicine for ulcer support and reflux.
Veterinary applications
Some integrative vets use DGL for canine gastric ulcer support.
Acid reflux support in some cases.
Recovery from gastritis.
Always under veterinary direction.
Evidence base
Human research substantial for ulcer and reflux support.
Direct canine research limited.
Use in dogs based largely on extrapolation from human research and clinical experience.
Discuss with your vet whether appropriate for your dog's specific situation.
Dosing
Typical doses: 100-200 mg per 25 pounds of body weight, two to three times daily.
Chewable tablet forms often used in humans — can be split for dogs.
Take 20-30 minutes before meals for best effect.
Discuss appropriate dosing with your vet.
Combining with other inputs
Often used alongside other gastric-supportive ingredients.
Slippery elm, marshmallow root, L-glutamine, zinc.
Each addresses different aspects of gastric health.
Multi-ingredient approaches often more comprehensive.
Combining with prescription medications
DGL is sometimes used alongside acid suppressors (omeprazole, famotidine) for gastric support.
Discuss with your vet about whether combination is appropriate for your dog.
Generally well-tolerated combination but always confirm with vet.
Cautions
DGL is much safer than whole licorice but always confirm DGL labeling.
Long-term use should still be monitored.
Dogs with cardiovascular conditions — discuss with vet.
Pregnant and nursing dogs — limited safety data.
What DGL doesn't do
Replace acid suppressors when those are indicated.
Treat infectious causes of gastritis (Helicobacter, parasites).
Substitute for veterinary care in serious gastric disease.
Discuss with your vet about appropriate role in comprehensive care.
Quality considerations
Look for products specifying DGL (deglycyrrhizinated) rather than whole licorice.
Standardized for specific compound content where possible.
Skip products that pad the ingredient list with unnecessary additives.
Third-party testing helpful.
Form considerations
Chewable tablets work well for dogs.
Powder form can be mixed with food.
Some combination products include DGL among other GI ingredients.
Common questions about DGL
Is DGL safe for long-term use? Generally yes — the removal of glycyrrhizin addresses the main safety concern.
Can I use whole licorice instead? Generally not recommended for sustained use due to side effects.
Will DGL cure ulcers? Supportive, not curative. Used alongside medical treatment.
Can I use human DGL products? Often yes, with dosing adjusted by weight. Discuss with your vet.
What to track at home
GI symptoms and any changes.
Response to treatment overall.
Any side effects.
Discuss with your vet at follow-up visits.
Where our formulas fit
For dogs in ongoing gastric support under your vet's direction, a daily multi-ingredient GI blend can complement specific therapeutic ingredients like DGL. For ongoing management of ulcer recovery and gastric inflammation under vet care, G.I. Balance is the everyday-routine option — formulated for daily use without the harsh effect of rescue-style interventions.
Related reading
The bottom line
The owners we hear from longest are the ones who didn't expect miracles. They expected steady support and got it. We'd rather build that kind of relationship than chase the next viral claim.